Lynne I. Wagner, PhD
Department of Medical Social Sciences
Department of Psychiatry and Behavioral Sciences
Northwestern University Feinberg School of Medicine
Member, Robert H. Lurie Comprehensive Cancer Center of Northwestern University (RHLCCC)
Director, Supportive Oncology at RHLCCC at the Northwestern Medical Faculty Foundation
633 N. Saint. Clair St., 19th Fl.
Chicago, IL 60611
The focus for my clinical research is on improving quality of life for adults with cancer through conducting research in cancer symptom management, developing and validating patient-reported outcomes measures to assess quality of life from the patient perspective, and measuring patient-reported outcomes in cancer clinical trials. A large focus of my research is on understanding the trajectory of cognitive function throughout treatment for cancer (ie. “chemo-brain”) and developing a questionnaire and an item bank to assess perceived cognitive function. Building on my graduate school research on chronic fatigue, I have conducted research on cancer-related fatigue including the evaluation of single-item screening for fatigue and clinical management of fatigue. I serve as an expert panel member on the National Comprehensive Cancer Network Cancer-Related Fatigue Panel and on the Distress Management Panel. As Co-Chair of the Eastern Cooperative Oncology Group Patient Outcomes and Survivorship Committee, I serve as the lead investigator or co-investigator on cancer clinical trials to assess health-related quality of life throughout treatment for various types of cancer, including breast cancer, gastrointestinal cancer, and lymphoma.
I am a Clinical Health Psychologist and I provide psychosocial oncology clinical services through RHLCCC adult oncology clinics. I utilize evidence-based approaches for the cognitive behavioral management of anxiety, depression and cancer-related symptoms with adults who have all types of cancer, from diagnosis through cancer survivorship. My clinical interests include utilizing mind-body strategies for the management of fear of recurrence, anxiety, and cancer-related symptoms (eg. fatigue, “chemo-brain”). I am currently the Director of our Supportive Oncology team at RHLCCC, where I provide leadership for our inter-disciplinary team of supportive oncology care providers, including psychologists, social workers, dietitians, and health information specialists.
Wagner, L.I., Sweet, J.S., Butt, Z., Lai, J.S., & Cella, D. (in press). Measuring patient self-reported cognitive function: Development of the Functional Assessment of Cancer Therapy – Cognitive Function instrument. Journal of Supportive Oncology.
Jacobsen, P. B., & Wagner, L. I. (2012). A new quality standard: the integration of psychosocial care into routine cancer care. Journal of Clinical Oncology, 30(11), 1154-1159
Lai, J.S., Butt, Z., Wagner, L., Sweet, J.J., Beaumont, J.L., Vardy, J., Jacobsen, P.B., Shapiro, P.J., Jacobs, S.R. & Cella, D. (2009). Evaluating the dimensionality of perceived cognitive function. Journal of Pain and Symptom Management, 37, 982-995.
Butt, Z., Wagner, L.I., Beaumont, J.L., Paice, J.A., Peterman, A.H., Shevrin, D., Von Roenn, J. H., Carro, G., Straus, J.L., Muir, J.C., & Cella, D. (2008). Use of a single-item screening tool to detect clinically significant fatigue, pain, distress, and anorexia in ambulatory cancer practice. Journal of Pain and Symptom Management, 35, 20-30.
Butt, Z., Wagner, L. I., Beaumont, J. L., Paice, J. A., Straus, J. L., Peterman, A. H., Carro, G., Von Roenn, J. H., Shevrin, D., & Cella, D. (2008). Longitudinal screening and management of fatigue, pain, and emotional distress associated with cancer therapy. Supportive Care in Cancer, 16, 151-159.
Wagner, L.I., Beaumont, J.L., Ding, B., Malin, J., Peterman, A., Calhoun, E., & Cella, D. (2008). Measuring health-related quality of life and neutropenia-specific concerns among older adults undergoing chemotherapy: Validation of the Functional Assessment of Cancer Therapy – Neutropenia (FACT-N). Supportive Care in Cancer, 16, 47-56.
Jacobs, S. R., Jacobsen, P. B., Booth-Jones, M., Wagner, L. I., & Anasetti, C. (2007). Evaluation of the Functional Assessment of Cancer Therapy Cognitive Scale with hematopoetic stem cell transplant patients. Journal of Pain and Symptom Management, 33, 13-33.
Cella, D., Wagner, L., Cashy, J., Hensing, T., Yount, S., & Lilenbaum, R. (2007). Should health-related quality of life be measured in cancer symptom management clinical trials? Lessons learned using the Functional Assessment of Cancer Therapy (FACT). Journal of the National Cancer Institute, 37, 53-60.
Wagner, L.I. & Lacouture, M. (2007). Clinical psychologist’s perspective on dermatologic toxicities associated with EGFR inhibitors: Impact on health-related quality of life and implications for clinical management of psychological sequelae. Oncologist, 21, 34-36.
Wagner, L.I., Wenzel, L., Shaw, E., & Cella, D. (2007). Patient-reported outcomes in phase II clinical trials: Lessons learned and future directions. Journal of Clinical Oncology, 32, 5058-5062.
Joly, F., Alibhai, S.M., Galica, J., Park, A., Yi, Q.L., Wagner, L., & Tannock, I.F. (2006). Impact of androgen deprivation therapy on physical and cognitive function as well as quality of life of patients with nonmetastatic prostate cancer. Journal of Urology, 176, 2443-2447.
Vardy, J., Wong, K., Yi, Q., Park, A., Maruff, P., Wagner, L., & Tannock, I.F. (2006). Assessing cognitive function in cancer patients. Supportive Care in Cancer, 14, 1111-1118.
Paterson, A.G., Trask, P.C., Wagner, L.I., Esper, P., & Redman, B. (2005). Validation of the FACT-BRM with interferon-alpha treated melanoma patients. Quality of Life Research, 14, 133-139.
Davis, K., Yount, S., Wagner, L., & Cella, D. (2004). Measurement and management of health-related quality of life in lung cancer. Clinical Advances in Hematology & Oncology, 2, 533-540.
Wagner, L.I. & Cella, D. (2004). Fatigue in cancer: Causes, prevalence and treatment approaches. British Journal of Cancer, 91, 822-828.